Max Planck Institute of Colloids and Interfaces - Department of Biomaterials
The Department of Biomaterials focuses on interdisciplinary research in the field of biological and biomimetic materials. The emphasis is on understanding how the mechanical or other physical properties are governed by structure and composition and how they adopt to environmental conditions.
Extracellular matrix biophysical cues in breast cancer dormancy and bone metastasis
Aim. The overall goal is to contribute to the understanding of how biophysical mechanisms regulate
cell-matrix interaction in breast cancer dormancy and bone metastasis.
Tasks. The PhD candidate will perform correlative, multiscale characterization of the microstructure
and composition of the native early metastatic and dormant niche in-vivo and ex-vivo.
His/her tasks will be:
Work with in-vivo mouse models
In-vivo imaging by bioluminiscence and microcomputed tomography
Ex-vivo multiscale and multimodal tissue characterization
Profile. The applicant should have keen interest in multidisciplinary work and a strong drive to
excel in a competitive international research environment. A background in biochemistry, biotechnology, biophysics or a closely related field is required. Skills in imaging methods and characterization of biological tissues are of advantage. The project can be started September 2018 onwards. The working language is English.
What we offer:
Research team. Our team is interdisciplinary and investigates the influence of biomaterial physical
properties on cell behaviour, tissue regeneration and disease progression. We use a multiscale
and multimodal approach to characterize the properties of biological tissues. The project
will run in collaboration with Prof. David Mooney (Harvard University), Prof. Franziska Jundt
(Uniklinikum Würzburg), Prof. Claudia Fischbach (Cornell University), Prof. Georg Duda
(Charité University Hospital Berlin), Prof. Bettina Willie (McGill University) and Dr. Raluca
Niesner (DRFZ Berlin).
How to apply:
Please send a motivation letter explaining why you would like to join the project,
your CV, a transcript of your university record and two references to Amaia Cipitria
(firstname.lastname@example.org), indicating “Dormatrix - PhD application” in the subject