Charité - Universitätsmedizin Berlin - Medizinische Klinik m.S. Kardiologie
The Charité - Universitätsmedizin Berlin is a joint medical faculty, which serves both Freie Universität Berlin and Humboldt Universität zu Berlin. As one of the largest university hospitals in Europe with an important history, it plays a leading role in research, teaching and clinical care. The Charité university hospital has also made a name for itself as a modern business with certifications in the medical, clinical and management fields.
Post-doc Position in Cardiac Cellular Signaling
The Laboratory of Experimental Cardiology at Charité Universitätsmedizin Berlin is seeking a postdoctoral researcher for cellular heart failure and arrhythmia research. However, we are also encouraging talented people with different scientific background and interest to develop into this field.
The Heinzel group is focused on cardiomyocyte function and signaling in cardiac remodeling, heart failure and arrhythmias with a strong translational perspective, including different established rodent and large animal models as well as very regular access functional primary human myocardium and engineered heart tissue. The group is active member of the German Center for Cardiovascular Research (DZHK), site Berlin, and collaborates with academic institutions abroad as well as industry partners exploring novel pharmacological approaches.
Your area of responsibility:
This post-doctoral position in the Working Group of Prof. Frank Heinzel investigates cardiomyocyte and myocardial tissue function and signaling in heart failure. The project is embedded in a large long-term and multidisciplinary translational research project on heart failure research (Collaborative Research Center, Sonderforschungsbereich SFB 1470), which has just been established as an initiative of the Charité in co-operation with the Max Delbrück Center in Berlin. Working independently within a strong team, the candidate will investigate cellular mechanisms of contractile dysfunction and arrhythmias and the impact of cellular signaling on in vivo function, and explore novel therapeutic approches. The candidate may also participate in other funded projects of the group.
a PhD or equivalent doctoral training.
Experience in cardiovascular science, biology, biophysics, or a closely related field.
able to work independently in the setting of a strong and motivated team
experience in fluorescence microscopy (ratiometric and/or confocal)
experience or interest in cellular electrophysiology (e.g. multi-electode arrays, patch clamping, optical imaging)
worked with primary cell culture or iPSCs, adenoviral gene transfer
experience in in vivo cardiac phenotyping (echocardiography, EP-studies, hemodynamics) in rodents
knowledge of standard molecular biology techniques (qRT-PCR, RNA/DNA isolation and purification, transcriptome analysis)
organized individual with experience in design, implementation, analysis, and interpretation of laboratory experiments and in scientific writing
proficiency in scientific oral and written English communication
experience in training of graduate and undergraduate students
What we offer:
Please note that due to the current funding the position will be 100% (39h) until 31.01.2025 and thereafter 50% (19,5h, until 31.12.2025).
Scientific staff is given sufficient time to carry out their own scientific work in accordance with their employment relationship.
How to apply:
Applicants should include the following with their applications:
(1) short letter of motivation,
(2) Curriculum Vitae that includes education, academic positions/appointments
(3) detailed list of research skills
(4) complete list of publications
(5) contact information of up to three references.