Charité - Universitätsmedizin Berlin - CC02, Institut für Biochemie
The Charité - Universitätsmedizin Berlin is a joint medical faculty, which serves both Freie Universität Berlin and Humboldt Universität zu Berlin. As one of the largest university hospitals in Europe with an important history, it plays a leading role in research, teaching and clinical care. The Charité university hospital has also made a name for itself as a modern business with certifications in the medical, clinical and management fields.
The Rocks group "Systemic Cell Dynamics" at the Institute of Biochemistry combines cell and systems biological approaches with advanced fluorescence microscopy to investigate how cells change shape and move. These processes rely on Rho GTPase proteins that direct the cytoskeleton to generate mechanical forces.
We aim to understand how feedback interactions of the involved players at the plasma membrane create spatio-temporal signalling patterns that coordinate phenomena such as cell polarization, cell adhesion or directed cell migration. Our focus is on the RhoGEF and RhoGAP regulatory proteins, for which we have shown a key function in the control of cytoskeletal dynamics. We are looking for an enthusiastic candidate for a DFG-funded PostDoc or PhD position.